beta-Amino-1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid
3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid
CAS: 773123-81-2
Molecular Formula: C16H22N2O4
beta-Amino-1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid - Names and Identifiers
| Name | 3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid |
| Synonyms | 3-N-Cbz-amino-3-(4-piperidinyl)propionicacid 3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid 3-amino-3-(1-(benzyloxycarbonyl)piperidin-4-yl)propanoic acid 3-Amino-3-(1-(Benzyloxycarbonyl)Piperidin-4-Yl)Propanoic Acid 4-Piperidinepropanoicacid, b-aMino-1-[(phenylMethoxy)carbonyl]- 4-Piperidinepropanoic acid, β-amino-1-[(phenylmethoxy)carbonyl]- beta-Amino-1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid |
| CAS | 773123-81-2 |
| InChI | InChI=1/C16H22N2O4/c19-15(20)10-14(13-6-8-17-9-7-13)18-16(21)22-11-12-4-2-1-3-5-12/h1-5,13-14,17H,6-11H2,(H,18,21)(H,19,20) |
beta-Amino-1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid - Physico-chemical Properties
| Molecular Formula | C16H22N2O4 |
| Molar Mass | 306.36 |
| Density | 1.244 |
| Storage Condition | 2-8°C |
| Refractive Index | 1.547 |
beta-Amino-1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid - Introduction
3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid is an organic compound with a chemical formula of Cis -2-2-1-2-3-2-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-2-3-3-3-2-3-3-4-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3-3.
Nature:
-Appearance: A colorless solid
-melting point: about 130-135 ℃
-Solubility: Slightly soluble in water, soluble in polar organic solvents such as methanol, ethanol and dimethylformamide
Use:
3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid is commonly used as an intermediate in organic synthesis. It has a wide range of uses in the field of medicine, commonly used in the synthesis of drugs, pharmaceutical intermediates and peptide compounds.
Preparation Method:
In general, 3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid can be prepared by the following steps:
1. First, 4-piperidinecarboxylic acid is reacted with chloroacetic acid at reflux to form 4-(N-Cbz-4-piperidinyl) propionic acid.
2. Then, 4-(N-Cbz-4-piperidinyl) propionic acid is converted into 3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid by reduction or hydrolysis.
Safety Information:
3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid is a chemical that should be handled with care. Wear appropriate personal protective equipment, including chemical goggles, gloves and protective clothing during use and handling. Inhalation, swallowing and contact with skin should be avoided. Before use, please carefully read and follow the relevant chemical safety procedures.
Nature:
-Appearance: A colorless solid
-melting point: about 130-135 ℃
-Solubility: Slightly soluble in water, soluble in polar organic solvents such as methanol, ethanol and dimethylformamide
Use:
3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid is commonly used as an intermediate in organic synthesis. It has a wide range of uses in the field of medicine, commonly used in the synthesis of drugs, pharmaceutical intermediates and peptide compounds.
Preparation Method:
In general, 3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid can be prepared by the following steps:
1. First, 4-piperidinecarboxylic acid is reacted with chloroacetic acid at reflux to form 4-(N-Cbz-4-piperidinyl) propionic acid.
2. Then, 4-(N-Cbz-4-piperidinyl) propionic acid is converted into 3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid by reduction or hydrolysis.
Safety Information:
3-(N-Cbz-Piperidin-4-yl)-3-aminopropanoic acid is a chemical that should be handled with care. Wear appropriate personal protective equipment, including chemical goggles, gloves and protective clothing during use and handling. Inhalation, swallowing and contact with skin should be avoided. Before use, please carefully read and follow the relevant chemical safety procedures.
Last Update：2024-04-09 21:01:54
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